The institute has a graduate research program to which a group of students are admitted each year to work towards a Ph.D. degree. IMSc hosts scientists at the post-doctoral level and supports a visiting scientist program in areas of research in the institute.
Located in South Chennai, in the Adyar-Taramani area, the institute is on the Central Institutes of Technology (CIT) campus. The institute maintains a student hostel, flatlets for long-term visitors, married students and post-doctoral fellows, and the institute guest house. IMSc has its own faculty housing in Tiruvanmiyur near the seashore.