Methanol is extremely toxic to humans. If as little as 10 ml of pure methanol is ingested, for example, it can break down into formic acid, which can cause permanent blindness by destruction of the optic nerve, and 30 ml is potentially fatal,[2] although the median lethal dose is typically 100 ml (3.4 fl oz) (i.e. 1–2 ml/kg body weight of pure methanol.[3] This does not happen with ethanol, which breaks down into acetic acid, which is non-toxic in small amounts. Reference dose for methanol is 0.5 mg/kg/day.[4] Toxic effects take hours to start, and effective antidotes, like ethanol, can often prevent permanent damage.[2] Because of its similarities in both appearance and odor to ethanol (the alcohol in beverages), it is difficult to differentiate between the two.
Australia
In 2013 three people died and one suffered partial blindness when they ingested a home-made beverage containing methanol.[5]
In 1997 two people from Central Australia died and two survived after ingesting a drink made from methanol and other alcoholic beverages.[6]
Brazil
In 1999, 35 people died, in ten cities of the state of Bahia as a result of drinking cachaça contaminated with methanol. Further investigation revealed concentrations as high as 24.84% methanol. As other different cases have also been related, in a 20 day window there have been 450 people hospitalized with the toxicity symptoms of methanol ingestion.[7]
Cambodia
In 2012, 49 people died, and more than 300 people were hospitalized, after drinking rice wine contaminated by methanol.[8]
Costa Rica
25 persons died in August 2019 due to methanol poisoning.[9]
In El Salvador, as many as 122 people died in 2000 as a result of drinking low quality liquors sold in unauthorized shops that were found to be adulterated with methanol.[14] The incident prompted the authorities to declare a 10-day emergency prohibition and a massive inspection of alcohol-vending establishments. The root cause was believed to be an act of terrorism, possibly a social cleansing campaign targeted against alcoholics,[15] as the offending distilleries were not found to be responsible for the methanol contents that were present in the affected liquors.[16]
The Pärnu methanol poisoning incident occurred in Pärnu county, Estonia, in September 2001, when 68 people died and 43 were left disabled after contents of stolen methanol canisters were used in production of bootleg liquor.
2012: 18 people died in Gurdaspur district of Punjab in a possible methanol-poisoning incident. The Chemical Analyzer and Histo-pathology department took care of the bodies and will ascertain the exact cause of death.[22]
2017: On 3 January at least 6 people died at Ramgopalpur,[24]West Bengal
2019: In February 2019, 100 people in the northern states of Uttar Pradesh and Uttarakhand died by drinking toxic alcohol.[25]
2019: In February 2019, just days after the Uttar Pradesh and Uttarakhand deaths (above), 156 people (mostly tea plantation workers) died in Assam state. see 2019 Assam alcohol poisonings
In 2013, as a result of methanol mass poisoning in Iran[30] 694 people were hospitalised in the city of Rafsanjan. 8 people were reported dead due to severe intoxication.
Two men were killed in a methanol poisoning incident near to Burtonport, County Donegal, Republic of Ireland in 2014 after drinking what was claimed to be poitín (an Irish moonshine made from potatoes).[32] One man was native Irish and the other a Lithuanian immigrant. A bottle seized at the scene of one poisoning was found to contain 97% methanol.[33][34]
In 2017 a person was severely poisoned after buying "vodka" from an unlicensed seller in the Ballymun area of Dublin; the bottle had been refilled with a liquid containing methanol.[35][36][37]
At least 51 people died in Tripoli in 2013.[40] The consumption and sale of alcohol is illegal in Libya.[40]
Madagascar
The Madagascar methanol mass poisoning occurred in 1998 when 200 people died.[41]
Malaysia
From September until October 2018, 45 people have been reported died of methanol poisoning from drinking fake liquor.[42] In this incident, the methanol content was up to 50 times more than the permissible amount.[43] Cases of toxic alcohol poisoning have been reported in Selangor, the Federal Territories of Kuala Lumpur and Putrajaya, Perak and Negeri Sembilan.[42] The deaths comprised various nationalities mostly of foreign workers from Bangladesh, Indonesia, Myanmar and Nepal.[42] Around 30 people including three Indian nationals, believed to be responsible for the distribution of cheap counterfeit liquor to retailers around Selayang and Desa Jaya which led to the methanol poisoning incident have been arrested.[44][45]
Mexico
Government restrictions on liquor and beer sales during the COVID-19 pandemic may have exacerbated the problem of illegal production and sale of alcoholic beverages in Mexico. Reportedly, 35 people died in 2020 in just one mass poisoning incident due to methanol tainted drinks.[46]
Nigeria
Between April 14 and April 26, 2015, 23 deaths were recorded in relation to methanol poisoning in Ayadi and Ode-Irele towns of Irele Local Government Area in Ondo State.[47]
66 people in Rivers State died over a few weeks that started in April 2015 due to methanol-contaminated ogogoro.[48][49][50]
Norway
Between September 2002 and December 2004, 51 people were admitted to hospital with symptoms of methanol poisoning, of whom 9 died. A further 8 people who died outside hospital were found to have died from methanol poisoning following autopsy. The liquor responsible for all of the cases contained 20% methanol and 80% ethanol and probably came from the same source in southern Europe.[51]
Russia
Russian poster warning people about the dangers of drinking methanol.
In December 2016, 72 people died in a mass methanol poisoning in Irkutsk, Siberia. The poisoning was precipitated by drinking counterfeit surrogate alcohol—actually scented bath lotion that was marked as not safe for consumption.[52] Named Boyaryshnik ("Hawthorn"),[53] it was described by the Associated Press as being counterfeit.[54]
In October 2021, in Orenburg, 35 people died and 33 others were poisoned in a mass surrogate alcohol poisoning. 7 people were noted as being in serious condition, and 3 people were placed on ventilators. 10 people were arrested for the incident.[55]
Also in October 2021 18 people died and a number were poisoned in another mass surrogate alcohol poisoning in Yekaterinburg and towns nearby. Two persons were arrested.[56]
In 1963, methanol was used in the preparation of bottled mixed alcohol drinks such as coffee liqueur.
According official records, 51 died and 9 lost their sight, but according to newspapers there may have been thousands of victims, mainly in Galicia and the Canary Islands.[57][58]
In April 2010, 80 people died from multiple organ dysfunction syndrome after drinking waragi adulterated with a high amount of methanol over a three-week period in Kabale District.[66][67][68] Many of the deaths were blamed on the reluctance of people to openly admit their relatives had been drinking it, allowing the abuse of the substance to continue.[67][68] When revelations came about houses were searched, with around 120 jerrycans uncovered.[68]
United States
In December 1963, a rash of 31 deaths in Philadelphia's homeless population was traced to a local store that knowingly sold Sterno to people for them to consume and get drunk.[69]
In January 2016, consumption of a mixture of Mountain Dew and methanol, referred to as Dewshine, resulted in the reported deaths of two Tennessee high school students.[70] The methanol in this case was believed to come from racing fuel.[71][72]
In April 2018 a Massachusetts man died after ingesting alcohol that was contaminated with methanol. The product consumed was labeled "Ethanol Extraction 95% ethanol and 5% water". An FDA recall was issued and the company is no longer selling the product which was sold over the internet and shipped by the U.S. Postal Service.[citation needed]
^Williams, Gerald F.; Hatch, Fay J.; Bradley, Michael C. (1 December 1997). "Methanol poisoning: a review and case study of four patients from Central Australia". Australian Critical Care. 10 (4): 113–118. doi:10.1016/S1036-7314(97)70412-0. PMID9708069.
