This article needs additional citations for verification. Please help improve this article by adding citations to reliable sources. Unsourced material may be challenged and removed.Find sources: "Thienobenzodiazepine" – news · newspapers · books · scholar · JSTOR (May 2023) (Learn how and when to remove this template message)
General structure of thienobenzodiazepines. Core is highlighted by black and color. Grey depicts accessory functional groups.
General structure of thienobenzodiazepines. Core is highlighted by black and color. Grey depicts accessory functional groups.

Thienobenzodiazepine is a heterocyclic compound containing a diazepine ring fused to a thiophene ring and a benzene ring. Thienobenzodiazepine forms the central core of pharmaceutical drugs including atypical antipsychotic olanzapine (Zyprexa) and antimuscarinic telenzepine. Thienobenzodiazepines act relatively selectively at the α2 subunit of the GABAA receptor.[1]

References

  1. ^ Bymaster, Frank P; Calligaro, David O; Falcone, Julie F; Marsh, Richard D; Moore, Nicholas A; Tye, Nicholas C; Seeman, Philip; Wong, David T (February 1996). "Radioreceptor Binding Profile of the Atypical Antipsychotic Olanzapine". Neuropsychopharmacology. 4 (2): 87–96 – via PubMed.


Categories