17 September 2006 (Sunday)
- National Football League Week 2:
- Cincinnati Bengals 34, Cleveland Browns 17
- Buffalo Bills 16, Miami Dolphins 6
- Minnesota Vikings 16, Carolina Panthers 13 (OT)
- Chicago Bears 34, Detroit Lions 7
- Indianapolis Colts 43, Houston Texans 24
- New York Giants 30, Philadelphia Eagles 24 (OT): The G-men come from a 17-point deficit – aided by an ill-advised personal foul against the Eagles – and win on a Plaxico Burress 31-yard touchdown pass from Eli Manning.
- Baltimore Ravens 28, Oakland Raiders 6
- Atlanta Falcons 14, Tampa Bay Buccaneers 3: For the third time in NFL history, a quarterback (Michael Vick) and a running back (Warrick Dunn) each get 100 yards rushing. The Philadelphia Eagles turned the trick twice before in 1990 and 2002.
- Seattle Seahawks 21, Arizona Cardinals 10
- San Francisco 49ers 20, St. Louis Rams 13
- Denver Broncos 9, Kansas City Chiefs 6 (OT)
- New England Patriots 24, New York Jets 17: Eric Mangini loses to his teacher Bill Belichick.
- San Diego Chargers 40, Tennessee Titans 7
- Dallas Cowboys 24, Washington Redskins 10: The Cowboys win, but Terrell Owens is lost for between three and five weeks with a broken hand.
- Cycling: Alexander Vinokourov wins the 2006 Tour of Spain.
- Tennis: The second day of the 2006 Fed Cup Final takes place in Charleroi, with the score 1–1 after the previous day. The game is decided in the fifth and final match, the doubles, when Justine Henin-Hardenne is forced to retire through injury making Italy the 2006 Fed Cup winners.
Belgium 2–3
Italy:
- Basketball:
- Rugby union
Auto racing: Kevin Harvick wins the Sylvania 300 as the 2006 Chase for the NEXTEL Cup starts.