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Substituted piperazines are a class of chemical compounds based on a piperazine core. Some are used as recreational drugs and some are used in scientific research.

List of substituted piperazines


See also: Benzylpiperazine § Chemical derivatives

Befuraline, fipexide, and piberaline produce benzylpiperazine as a metabolite.


See also: Phenylpiperazine


Enpiprazole is known to produce oCPP as a metabolite.

Enciprazine was initially anticipated to produce oMeOPP as a metabolite, but this turned out not to be the case.


Trazodone, nefazodone, mepiprazole, and others produce mCPP as a metabolite.


Multiple substitutions


Other arylpiperazines

Many azapirones such as buspirone, gepirone, and tandospirone produce 1-PP as a metabolite.

See also