Etomethazene

Identifiers
IUPAC name 2-[(4-ethoxyphenyl)methyl]-N,N-diethyl-5-methyl-1H-benzimidazole-1-ethanamine
PubChem CID	168310446
Chemical and physical data
Formula	C23H31N3O
Molar mass	365.521 g·mol−1
3D model (JSmol)	Interactive image
SMILES CCOc3ccc(Cc2nc1cc(C)ccc1n2CCN(CC)CC)cc3
InChI InChI=1S/C23H31N3O/c1-5-25(6-2)14-15-26-22-13-8-18(4)16-21(22)24-23(26)17-19-9-11-20(12-10-19)27-7-3/h8-13,16H,5-7,14-15,17H2,1-4H3 Key:ZARKNPABJGEAOQ-UHFFFAOYSA-N

Etomethazene (5-methyldesnitroetonitazene) is a benzimidazole derivative with opioid effects which has been sold as a designer drug over the internet since early 2022. It is an analogue of etonitazene where the nitro (NO₂) group has been replaced by a methyl (CH₃) group. While formal studies into its pharmacology have yet to be carried out, it showed far less potency than etonitazene itself. Etomethazene has a potency around 20 times than morphine with a relatively short duration about 120 min.^[1][2]