Caswell No. 213B
3D model (JSmol)
CompTox Dashboard (EPA)
|Molar mass||285.8 g/mol|
|Appearance||odorless, white powder|
|Melting point||230-235 °C|
|Solubility in Chloroform, Benzene||soluble|
|Occupational safety and health (OHS/OSH):|
|Lethal dose or concentration (LD, LC):|
LD50 (median dose)
|1-4 mg/kg (rats, oral)|
3000 mg/kg (rats, dermal)
0.9-2.0 mg/kg (mice, oral)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
1-(4-Chlorophenyl)silatrane is an extremely toxic organosilicon compound which was developed by M&T Chemicals as a single-dose rodenticide. It was never registered as rodenticide, except for experimental use. 1-(4-Chlorophenyl)silatrane was one of the chemicals studied in the Project Coast.
1-(4-Chlorophenyl)silatrane is a GABA receptor antagonist and it destroys nervous functions in the central nervous system of vertebrates, primarily in the brain and possibly in the brain stem. It's a rapid acting convulsant, causing convulsions within 1 minute in mice and rats. Death occurred within 5 minutes. It is therefore likely to induce poison shyness. In field trials, it was less effective than zinc phosphide against wild rats.