• N-[(3R)-1-azabicyclo[2.2.2]oct-3-yl]-2-(1-methyl-1H-indol-3-yl)-2-oxoacetamide
CAS Number
PubChem CID
CompTox Dashboard (EPA)
Chemical and physical data
Molar mass311.385 g·mol−1
3D model (JSmol)
  • c14ccccc4n(C)cc1C(=O)C(=O)NC2CN3CCC2CC3

RS-56812 is a potent and selective partial agonist at the 5HT3 receptor.[1] It has been shown to improve performance on animal tests of memory. Its use in humans is not well documented. [2]


  1. ^ Van Hooft JA, Vijverberg HP (March 1997). "RS-056812-198: partial agonist on native and antagonist on cloned 5-HT3 receptors". European Journal of Pharmacology. 322 (2–3): 229–33. doi:10.1016/s0014-2999(96)00993-4. PMID 9098692.
  2. ^ Terry AV, Buccafusco JJ, Prendergast MA, Jackson WJ, Fontana DL, Wong EH, et al. (December 1996). "The 5-HT3 receptor antagonist, RS-56812, enhances delayed matching performance in monkeys". NeuroReport. 8 (1): 49–54. doi:10.1097/00001756-199612200-00011. PMID 9051751. S2CID 42903427.