|Chemical and physical data|
|Molar mass||379.504 g·mol−1|
|3D model (JSmol)|
1P-LSD or 1-propionyl-lysergic acid diethylamide is a psychedelic drug of the lysergamide class that is a derivative and functional analogue of LSD and a homologue of ALD-52. It has been sold online as a designer drug since 2015. It modifies the LSD molecule by adding a propionyl group to the nitrogen molecule of LSD's indole.
Since LSD is detected when 1P-LSD is incubated in human serum, 1P-LSD acts, at least in part, as a prodrug for LSD.
The effects profile of 1P-LSD is not well defined in the scientific literature. It is generally thought to be comparable to that of LSD. Many anecdotal reports indicate that 1P-LSD has a slightly shorter duration than LSD in humans, with the majority of users stating that they cannot distinguish the qualitative effects of 1P-LSD from LSD.
1P-LSD is a controlled substance in France, Finland, Denmark, Germany, Estonia, Japan, Latvia, Norway, Romania, Sweden, Switzerland, United Kingdom, Italy, Singapore and the Czech Republic (banned in 2018).