|CompTox Dashboard (EPA)|
|Chemical and physical data|
|Molar mass||267.170 g·mol−1|
|3D model (JSmol)|
5-Bromo-DMT (5-bromo-N,N-dimethyltryptamine) is a psychedelic brominated indole alkaloid found in the sponges Smenospongia aurea and Smenospongia echina, as well as in Verongula rigida (0.00142% dry weight) alongside 5,6-Dibromo-DMT (0.35% dry weight) and seven other alkaloids. It is the 5-bromo derivative of DMT, a psychedelic found in many plants and animals.
5-Bromo-DMT has a pEC50 value of 5.51 for the 5-HT2A receptor.
Animal studies on 5-Bromo-DMT showed that it produces effects suggestive of sedative and antidepressant activity and caused significant reduction of locomotor activity in the rodent FST model.
5-Bromo-DMT was reported to be psychoactive at 20–50 mg via vaporization with mild psychedelic-like activity.
5-Bromo-DMT is specifically listed as a controlled drug in Singapore.