2C-T-28
2CT28 structure.png
Names
Preferred IUPAC name
2-[4-(3-fluoropropylsulfanyl)-2,5-dimethoxyphenyl]ethanamine
Identifiers
3D model (JSmol)
  • InChI=1S/C13H20FNO2S/c1-16-11-9-13(18-7-3-5-14)12(17-2)8-10(11)4-6-15/h8-9H,3-7,15H2,1-2H3
    Key: XAFVGDRNPGLCMI-UHFFFAOYSA-N
  • COC1=CC(=C(C=C1CCN)OC)SCCCF
Properties
C13H20FNO2S
Molar mass 273.37 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

2C-T-28 is a lesser-known psychedelic drug related to compounds such as 2C-T-7 and 2C-T-21. It was named by Alexander Shulgin but was never made or tested by him, and was instead first synthesised by Daniel Trachsel some years later. It has a binding affinity of 75nM at 5-HT2A and 28nM at 5-HT2C. It is reportedly a potent psychedelic drug with an active dose in the 8–20 mg range, and a duration of action of 8–10 hours, with prominent visual effects. 2C-T-28 is the 3-fluoropropyl instead of 2-fluoroethyl chain-lengthened homologue of 2C-T-21 and has very similar properties, although unlike 2C-T-21 it will not form toxic fluoroacetate as a metabolite.[1][2]

See also

References

  1. ^ Shulgin A, Manning T, Daley PF (2011). The Shulgin Index. Volume 1. Psychedelic Phenethylamines and Related Compounds. Transform Press. p. 346. ISBN 978-0-9630096-3-0.
  2. ^ Trachsel D, Lehmann D, Enzensperger C (2013). Phenethylamine: Von der Struktur zur Funktion. Nachtschatten Verlag AG. pp. 789–794. ISBN 978-3-03788-700-4.