G protein-coupled receptor, family C, group 5, member A | |||||||
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Identifiers | |||||||
Symbol | GPRC5A | ||||||
Alt. symbols | RAIG1, RAI3 | ||||||
NCBI gene | 9052 | ||||||
HGNC | 9836 | ||||||
OMIM | 604138 | ||||||
RefSeq | NM_003979 | ||||||
UniProt | Q8NFJ5 | ||||||
Other data | |||||||
Locus | Chr. 12 p13-p12.3 | ||||||
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G protein coupled receptor, family C, group 5, member B | |||||||
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Identifiers | |||||||
Symbol | GPRC5B | ||||||
Alt. symbols | RAIG2 | ||||||
NCBI gene | 51704 | ||||||
HGNC | 13308 | ||||||
OMIM | 605948 | ||||||
RefSeq | NM_016235 | ||||||
UniProt | Q9NZH0 | ||||||
Other data | |||||||
Locus | Chr. 16 p12 | ||||||
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G protein-coupled receptor, family C, group 5, member C | |||||||
---|---|---|---|---|---|---|---|
Identifiers | |||||||
Symbol | GPRC5C | ||||||
Alt. symbols | RAIG3 | ||||||
NCBI gene | 55890 | ||||||
HGNC | 13309 | ||||||
OMIM | 605949 | ||||||
RefSeq | NM_022036 | ||||||
UniProt | Q9NQ84 | ||||||
Other data | |||||||
Locus | Chr. 17 q25 | ||||||
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G protein-coupled receptor, family C, group 5, member D | |||||||
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Identifiers | |||||||
Symbol | GPRC5D | ||||||
NCBI gene | 55507 | ||||||
HGNC | 13310 | ||||||
OMIM | 607437 | ||||||
RefSeq | NM_018654 | ||||||
UniProt | Q9NZD1 | ||||||
Other data | |||||||
Locus | Chr. 12 p13.3 | ||||||
|
The Retinoic Acid-Inducible orphan G-protein-coupled receptors (RAIG) are a group of four closely related G protein-coupled receptors whose expression is induced by retinoic acid.[1][2][3][4]
The exact function of these proteins has not been determined but they may provide a mechanism by which retinoic acid can influence G protein signal transduction cascades. In addition, RAIG receptors interact with members of the frizzled class of G protein-coupled receptors and appear to activate the Wnt signaling pathway.[5]