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Trade names | Benedorm, Didropyridine, Dihydroprylone, Persedon, Presidon, Pyridion, Pyridione, Pyrithyldion, Pyrithyldione, Tetridin, Tetridine |
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ECHA InfoCard | 100.000.910 |
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Formula | C9H13NO2 |
Molar mass | 167.208 g·mol−1 |
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NY (what is this?) (verify) |
Pyrithyldione[1] (Presidon, Persedon) is a psychoactive drug invented in 1949.[2] An improved method of manufacture was patented by Roche in 1959.[3] It was used as a hypnotic or sedative and presumed to be less toxic than barbiturates.[4] Today, this substance is no longer used. Agranulocytosis was sometimes reported as adverse effect.[5][6] Pyrithyldione is also a CYP2D6 inducer but is not as potent as glutethimide[7] In studies, it increased the O-Demethylation of codeine by 20%.
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