Clinical data
AHFS/Drugs.comInternational Drug Names
ATC code
Legal status
Legal status
  • 2,2,2-trichloroethanol dihydrogen phosphate
CAS Number
PubChem CID
CompTox Dashboard (EPA)
ECHA InfoCard100.005.624 Edit this at Wikidata
Chemical and physical data
Molar mass229.37 g·mol−1
3D model (JSmol)
  • ClC(Cl)(Cl)COP(=O)(O)O
  • InChI=1S/C2H4Cl3O4P/c3-2(4,5)1-9-10(6,7)8/h1H2,(H2,6,7,8) checkY
 ☒NcheckY (what is this?)  (verify)

Triclofos is a sedative drug used rarely for treating insomnia.[2]

Triclofos is a prodrug which is metabolised in the liver into the active drug trichloroethanol. The half-life of triclofos is fairly long and it may cause drowsiness the next day. Trichloroethanol may cause liver damage and triclofos should not be used for extended periods.

Triclofos is no longer available in the United States.[3]

Side effects

Side effects may include:


  1. ^ Anvisa (2023-03-31). "RDC Nº 784 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial" [Collegiate Board Resolution No. 784 - Lists of Narcotic, Psychotropic, Precursor, and Other Substances under Special Control] (in Brazilian Portuguese). Diário Oficial da União (published 2023-04-04). Archived from the original on 2023-08-03. Retrieved 2023-08-16.
  2. ^ Erhorn S (2007). "Triclofos". xPharm: The Comprehensive Pharmacology Reference. Elsevier. pp. 1–4. doi:10.1016/B978-008055232-3.62797-7. ISBN 978-0-08-055232-3. Retrieved 29 February 2020.
  3. ^ "Drugs@FDA: FDA-Approved Drugs". Retrieved 29 February 2020.