Human spaceflights were vital to the operation of Mir, allowing crews and equipment to be carried to and from the space station. Mir was visited by a total of 39 crewed missions, comprising 30 Soyuz flights (1 Soyuz-T, 29 Soyuz-TM) and 9 Space Shuttle flights. These missions carried both long-duration crew members flying principal expeditions (ranging from 70 days up to Valeri Polyakov's 14-month stay beginning in January 1994, which still holds the record for the longest continuous spaceflight by a single person) and short-term visitors (who spent about a week aboard the station). Many of the crew who visited Mir used different spacecraft to launch than they did to land; the first such examples were Aleksandr Viktorenko and Muhammed Faris who flew up in Soyuz TM-3 (launched 22 July 1987) and landed a week later in Soyuz TM-2 on 30 July 1987. The largest crew aboard Mir simultaneously (not including Shuttle-Mir missions) was 6, which first occurred with the launch of Soyuz TM-7 on 26 November 1988 and lasted for just over three weeks.

In this list, uncrewed visiting spacecraft are excluded (see List of uncrewed spaceflights to Mir for details), and long-duration crew members are listed in bold. Times are given in Coordinated Universal Time (UTC). "Time docked" refers to the spacecraft and does not necessarily correspond to the crew.

#	Mission	Launch date (UTC)	Time docked	Landing date (UTC)	Launch crew	Crew photo	Crew patch	Notes
1.	Soyuz T-15	13 March 1986 12:33:09	~52 days ~20 days	16 July 1986 12:34:05	Leonid Kizim Vladimir Solovyov			Delivered the first crew, flying expedition EO-1, to Mir, then undocked, flew to and docked with Salyut 7 before returning to Mir. Remains the only spacecraft to have visited two space stations during one mission.[4][5]
2.	Soyuz TM-2	5 February 1987 21:38:16	~172 days	30 July 1987 01:04:12	Yuri Romanenko Aleksandr Laveykin			Delivered the second crew, flying expedition EO-2, to Mir.[4][5]
3.	Soyuz TM-3	22 July 1987 01:59:17	~158 days	29 December 1987 09:16:15	Aleksandr Aleksandrov Aleksandr Viktorenko Muhammed Faris			Delivered a third crew member, Aleksandrov, for EO-2, as well as the first Mir Intercosmos mission, EP-1, to the station. The EP-1 crew members, Viktorenko and Faris, returned to Earth aboard Soyuz TM-2 after 8 days.[4][5]
4.	Soyuz TM-4	21 December 1987 11:18:03	~177 days	17 June 1988 10:12:32	Vladimir Titov Musa Manarov Anatoli Levchenko			Delivered the third expedition crew, EO-3, to Mir, in addition to Anatoli Levchenko, who returned to Earth aboard Soyuz TM-3 with the returning EO-2 crewmembers after 8 days.[4][5]
5.	Soyuz TM-5	7 June 1988 14:03:13	~90 days	7 September 1988 00:49:38	Anatoly Solovyev Viktor Savinykh Aleksandr Aleksandrov			Delivered the second Mir Intercosmos mission, EP-2, to the station. All three crew returned to Earth aboard Soyuz TM-4 after 10 days.[4][5]
6.	Soyuz TM-6	29 August 1988 04:23:11	~112 days	21 December 1988 09:57:00	Valeri Polyakov Vladimir Lyakhov Abdul Ahad Mohmand			Delivered a third crew member, Polyakov, for EO-3, in addition to the third Mir Intercosmos crew, EP-3, who returned to Earth aboard Soyuz TM-5 after 9 days.[4][5]
7.	Soyuz TM-7	26 November 1988 15:49:34	~149 days	27 April 1989 02:57:58	Aleksandr Volkov Sergei Krikalev Jean-Loup Chrétien			Delivered the EO-4 and Aragatz crews to Mir, with Chrétien returning to Earth aboard Soyuz TM-6 after 25 days.[4][5]
8.	Soyuz TM-8	5 September 1989 21:38:03	~165 days	19 February 1990 04:36:18	Aleksandr Viktorenko Aleksandr Serebrov			Delivered the EO-5 crew to Mir.[4][5]
9.	Soyuz TM-9	11 February 1990 06:16:00	~177 days	9 August 1990 07:33:57	Anatoly Solovyev Aleksandr Balandin			Delivered the EO-6 crew to Mir.[4][5]
10.	Soyuz TM-10	1 August 1990 09:32:21	~129 days	10 December 1990 06:08:12	Gennadi Manakov Gennady Strekalov			Delivered the EO-7 crew to Mir.[4][5]
11.	Soyuz TM-11	1 December 1990 08:13:32	~173 days	26 May 1991 10:04:13	Viktor Afanasyev Musa Manarov Toyohiro Akiyama			Delivered the EO-8 crew to Mir, in addition to the Japanese Kosmoreporter mission. Akiyama, who became the first Japanese citizen to fly in space, returned to Earth aboard Soyuz TM-10 after 8 days.[4][5]
12.	Soyuz TM-12	18 May 1991 12:50:28	~142 days	10 October 1991 04:12:18	Anatoly Artsebarsky / Sergei Krikalev Helen Sharman			Delivered the EO-9 crew to Mir, in addition to the British Project Juno mission. Sharman, the first Briton to travel into space whilst not holding American citizenship, returned to Earth aboard Soyuz TM-11 after 8 days.[4][5]
13.	Soyuz TM-13	2 October 1991 05:59:38	~173 days	25 March 1992 08:51:22	/ Aleksandr Volkov Toktar Aubakirov Franz Viehböck			The last crewed spaceflight ever launched by the Soviet Union, Soyuz TM-13 delivered a third crew member to Mir for EO-10, in addition to carrying the first Austrian to go into space as part of the Austromir '91 mission. Aubakirov and Viehböck returned to Earth aboard Soyuz TMA-12 after 8 days.[4][5]
14.	Soyuz TM-14	17 March 1992 10:54:30	~143 days	10 August 1992 01:05:02	Aleksandr Viktorenko Aleksandr Kaleri Klaus-Dietrich Flade			The first crewed spaceflight to be launched by the Russian Federation, Soyuz TM-14 delivered the EO-11 crew to Mir, in addition to Flade, flying the German Mir '92 mission, who returned to Earth aboard Soyuz TM-13 after 8 days.[4][5]
15.	Soyuz TM-15	27 July 1992 06:08:42	~187 days	1 February 1993 03:49:57	Anatoly Solovyev Sergei Avdeyev Michel Tognini			Delivered the EO-12 crew to Mir, in addition to the French Antarès mission. Tognini returned to Earth aboard Soyuz TM-14 after 14 days.[4][5]
16.	Soyuz TM-16	24 January 1993 05:58:05	~177 days	22 July 1993 06:41:50	Gennadi Manakov Aleksandr Poleshchuk			Delivered the EO-13 crew to Mir. Became the only Soyuz spacecraft to dock at Kristall's distal APAS-89 port in order to check the port in preparation for the Shuttle-Mir flights which followed.[4][5]
17.	Soyuz TM-17	1 July 1993 14:32:58	~195 days	14 January 1994 08:18:20	Vasili Tsibliyev Aleksandr Serebrov Jean-Pierre Haigneré			Delivered the EO-14 crew to Mir, in addition to the French Altair mission. Haigneré returned to Earth aboard Soyuz TM-16 after 21 days.[4][5]
18.	Soyuz TM-18	8 January 1994 10:05:34	~180 days	9 July 1994 10:32:35	Viktor Afanasyev Yury Usachev Valeri Polyakov			Delivered the EO-15 crew to Mir, with Polyakov remaining in space for over 437 days, the current world record for longest single spaceflight.[4][5]
19.	Soyuz TM-19	1 July 1994 12:24:50	~124 days	4 November 1994 11:18:26	Yuri Malenchenko Talgat Musabayev			Delivered the EO-16 crew to Mir.[4][5]
20.	Soyuz TM-20	3 October 1994 22:42:30	~166 days	22 March 1995 04:04:05	Aleksandr Viktorenko Yelena Kondakova Ulf Merbold			Delivered the EO-17 crew to Mir, in addition to the German Euromir '94 mission. Merbold returned to Earth aboard Soyuz TM-19 after 32 days.[4][5]
21.	Soyuz TM-21	14 March 1995 06:11:34	~179 days	11 September 1995 06:52:40	Vladimir Dezhurov Gennady Strekalov Norman E. Thagard			Delivered the EO-18 crew to Mir, including Thagard, flying the first US long-duration mission of the Shuttle-Mir programme. The entire crew returned to Earth aboard Space Shuttle Atlantis at the conclusion of STS-71.[4][5]
22.	STS-71 Atlantis	27 June 1995	4 days, 22 hours		Robert L. Gibson Charles J. Precourt Ellen S. Baker Bonnie J. Dunbar Gregory J. Harbaugh Anatoly Solovyev Nikolai Budarin			Delivered Mir EO-19 crew Returned Mir EO-18 crew
23.	Soyuz TM-22	3 September 1995 09:00:23	~177 days	29 February 1996 10:42:08	Yuri Gidzenko Sergei Avdeyev Thomas Reiter			Delivered the EO-20 crew to Mir, including the German Euromir '95 mission.[4][5]
24.	STS-74 Atlantis	12 November 1995	3 days, 2 hours		Kenneth D. Cameron James D. Halsell Jerry L. Ross William S. McArthur Chris A. Hadfield			Delivered Mir Docking Module & Solar Array Package
25.	Soyuz TM-23	21 February 1996 12:34:05	~192 days	2 September 1996 07:41:40	Yuri Onufrienko Yury Usachev			Delivered the EO-21 crew to Mir.[4][5]
26.	STS-76 Atlantis	22 March 1996	4 days, 23 hours		Kevin P. Chilton Richard A. Searfoss Linda M. Godwin Michael R. Clifford Ronald M. Sega Shannon W. Lucid			Delivered Lucid for Mir EO-21 crew Deployed MEEP 1 spacewalk
27.	Soyuz TM-24	17 August 1996 13:18:03	~195 days	2 March 1997 06:44:16	Valery Korzun Aleksandr Kaleri Claudie Haigneré			Delivered the EO-21 crew to Mir. Haigneré returned to Earth aboard Soyuz TM-23 after 16 days.[4][5]
28.	STS-79 Atlantis	16 September 1996	4 days, 22 hours		William F. Readdy Terrence W. Wilcutt Thomas D. Akers Jerome Apt Carl E. Walz John E. Blaha			Delivered Blaha for Mir EO-22 crew
29.	STS-81 Atlantis	12 January 1997	4 days, 22 hours		Michael A. Baker Brent W. Jett John M. Grunsfeld Marsha S. Ivins Peter J.K. Wisoff Jerry M. Linenger			Delivered Linenger for Mir EO-22 crew
30.	Soyuz TM-25	10 February 1997 14:09:30	~183 days	14 August 1997 12:17:10	Vasili Tsibliyev Aleksandr Lazutkin Reinhold Ewald			Delivered the EO-23 crew to Mir. Ewald returned to Earth aboard Soyuz TM-24 after 20 days.[4][5]
31.	STS-84 Atlantis	15 May 1997	4 days, 23 hours		Charles J. Precourt Eileen M. Collins Carlos I. Noriega Edward T. Lu Jean-François Clervoy Yelena Kondakova Michael Foale			Delivered Foale for Mir EO-23 crew
32.	Soyuz TM-26	5 August 1997 15:35:54	~196 days	19 February 1998 09:10:30	Anatoly Solovyev Pavel Vinogradov			Delivered the EO-24 crew to Mir.[4][5]
33.	STS-86 Atlantis	27 September 1997	5 days, 22 hours		James D. Wetherbee Michael J. Bloomfield Scott E. Parazynski Wendy B. Lawrence Jean-Loup Chrétien Vladimir Titov David A. Wolf			Delivered Wolf for Mir EO-24 crew Retrieved MEEP 1 spacewalk
34.	STS-89 Endeavour	22 January 1998	4 days, 21 hours		Terrence W. Wilcutt Joe F. Edwards Bonnie J. Dunbar Michael P. Anderson James F. Reilly Salizhan Sharipov Andrew S.W. Thomas			Delivered Thomas for Mir EO-24 crew
35.	Soyuz TM-27	29 January 1998 16:33:42	~206 days	25 August 1998 05:24:44	Talgat Musabayev Nikolai Budarin			Delivered the EO-25 crew to Mir.
					Léopold Eyharts			Eyharts returned to Earth aboard Soyuz TM-26 after 22 days.[4][5]
36.	STS-91 Discovery	2 June 1998	3 days, 23 hours		Charles J. Precourt Dominic L. Pudwill Gorie Wendy B. Lawrence Franklin R. Chang-Diaz Janet L. Kavandi Valery Ryumin			Returned Thomas from Mir EO-25 crew
37.	Soyuz TM-28	13 August 1998 09:43:11	~196 days	28 February 1999 02:14:30	Gennady Padalka Sergei Avdeyev Yuri Baturin			Delivered the EO-26 crew to Mir. Baturin returned to Earth aboard Soyuz TM-27 after 12 days.[4][5]
38.	Soyuz TM-29	20 February 1999 04:18:01	~186 days	28 August 1999 00:34:20	Viktor Afanasyev Jean-Pierre Haigneré Ivan Bella			Delivered the EO-27 crew to Mir. Bella returned to Earth aboard Soyuz TM-28 after 8 days.[4][5]
39.	Soyuz TM-30	4 April 2000 05:01:29	~70 days	16 June 2000 00:44	Sergei Zalyotin Aleksandr Kaleri			Final human spaceflight to Mir. Delivered the last crew, flying EO-28.[4][5]