• (4-bromophenyl) 1,4-diazabicyclo[3.2.2]nonane-4-carboxylate
CAS Number
PubChem CID
Chemical and physical data
Molar mass329.232 g·mol−1
3D model (JSmol)
  • c1cc(ccc1OC(=O)N2CCN3CCC2CC3)Br
  • InChI=1S/C14H17BrN2O2/c15-11-1-3-13(4-2-11)19-14(18)17-10-9-16-7-5-12(17)6-8-16/h1-4,12H,5-10H2

SSR180711 is a drug that acts as a potent and selective partial agonist for the α7 subtype of neural nicotinic acetylcholine receptors.[1][2] In animal studies, it shows nootropic effects and may be useful in the treatment of schizophrenia.[3][4]


  1. ^ Pichat P, Bergis OE, Terranova JP, Urani A, Duarte C, Santucci V, et al. (January 2007). "SSR180711, a novel selective alpha7 nicotinic receptor partial agonist: (II) efficacy in experimental models predictive of activity against cognitive symptoms of schizophrenia". Neuropsychopharmacology. 32 (1): 17–34. doi:10.1038/sj.npp.1301188. PMID 16936709.
  2. ^ Biton B, Bergis OE, Galli F, Nedelec A, Lochead AW, Jegham S, et al. (January 2007). "SSR180711, a novel selective alpha7 nicotinic receptor partial agonist: (1) binding and functional profile". Neuropsychopharmacology. 32 (1): 1–16. doi:10.1038/sj.npp.1301189. PMID 17019409.
  3. ^ Hashimoto K, Ishima T, Fujita Y, Matsuo M, Kobashi T, Takahagi M, et al. (January 2008). "Phencyclidine-induced cognitive deficits in mice are improved by subsequent subchronic administration of the novel selective alpha7 nicotinic receptor agonist SSR180711". Biological Psychiatry. 63 (1): 92–7. doi:10.1016/j.biopsych.2007.04.034. PMID 17601496.
  4. ^ Barak S, Arad M, De Levie A, Black MD, Griebel G, Weiner I (June 2009). "Pro-cognitive and antipsychotic efficacy of the alpha7 nicotinic partial agonist SSR180711 in pharmacological and neurodevelopmental latent inhibition models of schizophrenia" (PDF). Neuropsychopharmacology. 34 (7): 1753–63. CiteSeerX doi:10.1038/npp.2008.232. PMID 19158670. S2CID 827363.