Clinical data
Routes of
Oral, Insufflation, Rectal
ATC code
  • none
Legal status
Legal status
  • (±)-2-amino-1-(3,4-methylenedioxyphenyl)propan-1-one
CAS Number
PubChem CID
Chemical and physical data
Molar mass193.202 g·mol−1
3D model (JSmol)
  • NC(C(=O)C1=CC2=C(C=C1)OCO2)C
  • InChI=1S/C10H11NO3/c1-6(11)10(12)7-2-3-8-9(4-7)14-5-13-8/h2-4,6H,5,11H2,1H3

3,4-Methylenedioxycathinone (also known as MDC, Nitrilone, Amylone and βk-MDA) is an empathogen and stimulant of the phenethylamine, amphetamine, and cathinone classes[1][2] and the β-keto analogue of MDA.[3]

Methylenedioxycathinone has been investigated as antidepressant and antiparkinson agent.[4]

See also


  1. ^ Zaitsu K, Katagi M, Tatsuno M, Sato T, Tsuchihashi H, Suzuki K (July 2011). "Recently abused β-keto derivatives of 3,4-methylenedioxyphenylalkylamines: a review of their metabolisms and toxicological analysis". Forensic Toxicology. 29 (2): 73–84. doi:10.1007/s11419-011-0111-8. S2CID 25416491.
  2. ^ Dal Cason TA, Young R, Glennon RA (December 1997). "Cathinone: an investigation of several N-alkyl and methylenedioxy-substituted analogs". Pharmacology, Biochemistry, and Behavior. 58 (4): 1109–16. doi:10.1016/S0091-3057(97)00323-7. PMID 9408221. S2CID 9704972.
  3. ^ Dal Cason TA (May 1997). "The characterization of some 3,4-methylenedioxycathinone (MDCATH) homologs". Forensic Science International. 87 (1): 9–53. doi:10.1016/S0379-0738(97)02133-6.
  4. ^ WO 1996039133, Jacob III P, Shulgin AT, "Preparation of novel N-substituted-2-amino-3′,4′-methylenedioxypropiophenones as anti-depressant and anti-parkinsonism agents.", published 12 December 1996, assigned to Neurobiological Technologies, Inc.