2C-B-BZP
2C-B-BZP.svg
2cbBZP3d.png
Legal status
Legal status
  • DE: NpSG (Industrial and scientific use only)
Identifiers
  • 1-[(4-Bromo-2,5-dimethoxyphenyl)methyl]piperazine
CAS Number
ChemSpider
UNII
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC13H19BrN2O2
Molar mass315.211 g·mol−1
3D model (JSmol)
  • C1(=CC(=C(C=C1CN2CCNCC2)OC)Br)OC
  • InChI=1S/C13H19BrN2O2/c1-17-12-8-11(14)13(18-2)7-10(12)9-16-5-3-15-4-6-16/h7-8,15H,3-6,9H2,1-2H3 checkY
  • Key:OHXVYXBOJDDYJS-UHFFFAOYSA-N checkY
 ☒NcheckY (what is this?)  (verify)

4-Bromo-2,5-dimethoxy-1-benzylpiperazine (2C-B-BZP) is a psychoactive drug and research chemical of the piperazine chemical class which has been sold as a "designer drug".[1][2] It produces stimulant effects similar to those of benzylpiperazine (BZP).

Chemistry

2C-B-BZP contains a benzylpiperazine base as well as the ring-substitution pattern of the psychedelic phenethylamine 2C-B. 2C-B-BZP is not a phenethylamine itself and does not produce psychedelic effects, as the binding groups are in the wrong position to activate the 5-HT2A receptor, while the phenylpiperazine homologue 2C-B-PP substitutes for DOM in DOM-trained rats with around one-tenth the potency of DOM, but does not substitute for TFMPP.[3]: 867–868 

Effects

2C-B-BZP produces stimulant effects which last 3–6 hours. It is also said by several sources to increase the effects of other compounds when combined[citation needed]. Side effects include headaches and nausea, similar to those of other recreationally-used piperazine derivatives.

Legality

2C-B-BZP is unscheduled and uncontrolled in the United States, but possession and sale of 2C-B-BZP could possibly be prosecuted under the Federal Analog Act because of its structural similarities to benzylpiperazine. 2C-B-BZP is illegal to possess, use or sell in Japan where it used to be sold in local smartshops.

See also

References

  1. ^ Westphal F, Junge T, Girreser U, Stobbe S, Pérez SB (May 2009). "Structure elucidation of a new designer benzylpiperazine: 4-bromo-2,5-dimethoxybenzylpiperazine". Forensic Science International. 187 (1–3): 87–96. doi:10.1016/j.forsciint.2009.03.003. PMID 19345524.
  2. ^ Peters FT, Martinez-Ramirez JA (October 2010). "Analytical toxicology of emerging drugs of abuse". Therapeutic Drug Monitoring. 32 (5): 532–9. doi:10.1097/FTD.0b013e3181f33411. PMID 20814349. S2CID 8009246.
  3. ^ Daniel Trachsel; David Lehmann & Christoph Enzensperger (2013). Phenethylamine: Von der Struktur zur Funktion. Nachtschatten Verlag AG. ISBN 978-3-03788-700-4.
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