Legal status
Legal status
  • 2-(methylamino)-1-(4-methylphenyl)-1-butanone
CAS Number
PubChem CID
CompTox Dashboard (EPA)
Chemical and physical data
Molar mass191.274 g·mol−1
3D model (JSmol)
  • CC1=CC=C(C(C(CC)NC)=O)C=C1.Cl
  • InChI=1S/C12H17NO.ClH/c1-4-11(13-3)12(14)10-7-5-9(2)6-8-10;/h5-8,11,13H,4H2,1-3H3;1H

4-Methylbuphedrone (also known as 4-MeMABP, BZ-6378 and 4-Methyl-α-methylamino-butyrophenone), is a stimulant drug of the cathinone class that has been sold online as a designer drug.[1][2][3]

It was first reported to the EMCDDA in November 2011.[4]

Legal status

4-Methylbuphedrone is listed in Anlage I and therefore illegal in Germany.

As of October 2015 4-MeMABP is a controlled substance in China.[5]

In the United States 4-Methylbuphedrone is considered a schedule 1 controlled substance as a positional isomer of 4-Methylethcathinone (4-MEC)[6]

See also


  1. ^ "4-Methylbuphedrone". Cayman Chemical. Retrieved 16 July 2015.
  2. ^ Uchiyama N, Matsuda S, Kawamura M, Kikura-Hanajiri R, Goda Y (January 2014). "Identification of two new-type designer drugs, piperazine derivative MT-45 (I-C6) and synthetic peptide Noopept (GVS-111), with synthetic cannabinoid A-834735, cathinone derivative 4-methoxy-α-PVP, and phenethylamine derivative 4-methylbuphedrine from illegal products". Forensic Toxicology. 32 (1): 9–18. doi:10.1007/s11419-013-0194-5. S2CID 37259772.
  3. ^ Uchiyama N, Kawamura M, Kikura-Hanajiri R, Goda Y (April 2013). "URB-754: a new class of designer drug and 12 synthetic cannabinoids detected in illegal products". Forensic Science International. 227 (1–3): 21–32. doi:10.1016/j.forsciint.2012.08.047. PMID 23063179.
  4. ^ Soussan C, Kjellgren A (September 2014). "Harm reduction and knowledge exchange-a qualitative analysis of drug-related Internet discussion forums". Harm Reduction Journal. 11 (25): 25. doi:10.1186/1477-7517-11-25. PMC 4160913. PMID 25200686.
  5. ^ "关于印发《非药用类麻醉药品和精神药品列管办法》的通知" (in Chinese). China Food and Drug Administration. 27 September 2015. Archived from the original on 1 October 2015. Retrieved 1 October 2015.
  6. ^ "Lists of: Scheduling Actions Controlled Substances Regulated Chemicals" (PDF). U.S. Department of Justice. February 2023. Retrieved 5 March 2023.