Legal status
Legal status
  • 2-(Ethylamino)-1-phenylbutan-1-one
CAS Number
PubChem CID
CompTox Dashboard (EPA)
Chemical and physical data
Molar mass191.274 g·mol−1
3D model (JSmol)
  • CCNC(CC)C(=O)c1ccccc1
  • InChI=1S/C12H17NO/c1-3-11(13-4-2)12(14)10-8-6-5-7-9-10/h5-9,11,13H,3-4H2,1-2H3

N-Ethylbuphedrone (also known as NEB) is a stimulant of the cathinone class that has been sold as a designer drug.[1][2][3][4] It is the β-ketone analogue of N,alpha-diethylphenylethylamine.

Legal status

As of October 2015 NEB is a controlled substance in China.[5]

In the United States NEB is considered a schedule 1 controlled substance as a positional isomer of 4-Methylethcathinone (4-MEC) [6]

See also


  1. ^ Lanza M, Acton WJ, Jürschik S, Sulzer P, Breiev K, Jordan A, et al. (September 2013). "Distinguishing two isomeric mephedrone substitutes with selective reagent ionisation mass spectrometry (SRI-MS)". Journal of Mass Spectrometry. 48 (9): 1015–1018. Bibcode:2013JMSp...48.1015L. doi:10.1002/jms.3253. PMID 24078242.
  2. ^ Acton WJ, Lanza M, Agarwal B, Jürschik S, Sulzer P, Breiev K, et al. (March 2014). "Headspace analysis of new psychoactive substances using a Selective Reagent Ionisation-Time of Flight-Mass Spectrometer". International Journal of Mass Spectrometry. 360: 28–38. Bibcode:2014IJMSp.360...28A. doi:10.1016/j.ijms.2013.12.009. PMC 4375562. PMID 25844048.
  3. ^ Uralets V, Rana S, Morgan S, Ross W (June 2014). "Testing for designer stimulants: metabolic profiles of 16 synthetic cathinones excreted free in human urine". Journal of Analytical Toxicology. 38 (5): 233–241. doi:10.1093/jat/bku021. PMID 24668489.
  4. ^ Pieprzyca E, Skowronek R, Czekaj P (November 2021). "Toxicological Analysis of Cases of Mixed Poisonings with Synthetic Cathinones and other Drugs of Abuse". Journal of Analytical Toxicology. 46 (9): 1008–1015. doi:10.1093/jat/bkab119. PMID 34849994.
  5. ^ "关于印发《非药用类麻醉药品和精神药品列管办法》的通知" (in Chinese). China Food and Drug Administration. 27 September 2015. Archived from the original on 1 October 2015. Retrieved 1 October 2015.
  6. ^ Diversion Control Division (February 2023). Lists of: Scheduling Actions; Controlled Substances; Regulated Chemicals (PDF) (Report). U.S. Department of Justice, Drug Enforcement Administration. Archived (PDF) from the original on 2023-03-06.