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| ECHA InfoCard | 100.113.606 |
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| Formula | C9H13NO3 |
| Molar mass | 183.207 g·mol−1 |
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Corbadrine (INN; marketed as Neo-Cobefrine), also known as levonordefrin (USAN) and α-methylnorepinephrine, is a catecholamine sympathomimetic used as a topical nasal decongestant and vasoconstrictor in dentistry in the United States,[1][2] (usually in a pre-mixed solution with local anesthetics, such as mepivacaine).[3]
Corbadrine is also a metabolite of the antihypertensive drug methyldopa,[4] and plays a role in its pharmacology and effects.
See also
[edit]References
[edit]- ^ Morton I, Morton IK, Hall JM (31 October 1999). Concise Dictionary of Pharmacological Agents: Properties and Synonyms. Springer Science & Business Media. pp. 164–. ISBN 978-0-7514-0499-9.
- ^ Index Nominum 2000: International Drug Directory. Taylor & Francis. January 2000. pp. 275–. ISBN 978-3-88763-075-1.
- ^ "DailyMed — Search results for levonordefrin". DailyMed. Retrieved 20 February 2016.
- ^ Sjoerdsma A, Vendsalu A, Engelman K (October 1963). "Studies on the Metabolism and Mechanism of Action of Methyldopa". Circulation. 28 (4): 492–502. doi:10.1161/01.CIR.28.4.492. PMID 14068757.
External links
[edit]- Nordefrin at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
Decongestants and other nasal preparations (R01) | |||||||||||
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| Systemic use: Sympathomimetics | |||||||||||
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| Amphetamines |
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| Phentermines |
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| Cathinones |
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| Phenylisobutylamines | |
| Phenylalkylpyrrolidines | |
| Catecholamines (and close relatives) |
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| Miscellaneous |
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