KSR1
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1KBE, 1KBF, 2LPE
Identifiers
Aliases	KSR1, KSR, RSU2, kinase suppressor of ras 1
External IDs	OMIM: 601132 MGI: 105051 HomoloGene: 8410 GeneCards: KSR1
Gene location (Human) Chr. Chromosome 17 (human)[1] Band 17q11.2 Start 27,456,448 bp[1] End 27,626,438 bp[1]
Gene location (Mouse) Chr. Chromosome 11 (mouse)[2] Band 11 B5|11 46.74 cM Start 78,904,266 bp[2] End 79,037,233 bp[2]
RNA expression pattern Bgee Top expressed in Body of pancreas sural nerve oocyte right lobe of thyroid gland canal of the cervix left lobe of thyroid gland gallbladder endothelial cell Stromal cell of endometrium secondary oocyte More reference expression data BioGPS More reference expression data
Gene ontology Molecular function metal ion binding protein C-terminus binding GO:0001948 protein binding ATP binding MAP-kinase scaffold activity protein kinase activity signal transducer activity mitogen-activated protein kinase kinase binding chaperone binding Hsp90 protein binding 14-3-3 protein binding Cellular component cytoplasm cytosol endoplasmic reticulum membrane membrane endoplasmic reticulum cell projection ruffle membrane plasma membrane protein-containing complex Biological process GO:0007243 intracellular signal transduction MAPK cascade cAMP-mediated signaling protein phosphorylation Ras protein signal transduction positive regulation of MAPK cascade regulation of cell population proliferation regulation of MAP kinase activity Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	8844	16706
Ensembl	ENSG00000141068	ENSMUSG00000018334
UniProt	Q8IVT5	Q61097
RefSeq (mRNA)	NM_014238 NM_001367810 NM_001394583 NM_001394584 NM_001394585	NM_013571 NM_001348207
RefSeq (protein)	NP_055053 NP_001354739	NP_001335136 NP_038599
Location (UCSC)	Chr 17: 27.46 – 27.63 Mb	Chr 11: 78.9 – 79.04 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

Kinase suppressor of Ras 1 is an enzyme that in humans is encoded by the KSR1 gene.^[5][6]