MAP3K9
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 3DTC, 4UY9
Identifiers
Aliases	MAP3K9, MEKK9, MLK1, PRKE1, mitogen-activated protein kinase kinase kinase 9
External IDs	OMIM: 600136 MGI: 2449952 HomoloGene: 76377 GeneCards: MAP3K9
Gene location (Human) Chr. Chromosome 14 (human)[1] Band 14q24.2 Start 70,722,526 bp[1] End 70,809,534 bp[1]
Gene location (Mouse) Chr. Chromosome 12 (mouse)[2] Band 12|12 D1 Start 81,767,784 bp[2] End 81,827,949 bp[2]
RNA expression pattern Bgee Top expressed in cerebellum dorsolateral prefrontal cortex vagina subthalamic nucleus brain postcentral gyrus More reference expression data BioGPS More reference expression data
Gene ontology Molecular function transferase activity nucleotide binding protein kinase activity protein homodimerization activity kinase activity protein serine/threonine kinase activity GO:0001948 protein binding ATP binding MAP kinase kinase kinase activity MAP kinase kinase activity JUN kinase kinase kinase activity Cellular component cytoplasm cellular component intracellular anatomical structure Biological process regulation of transcription, DNA-templated phosphorylation cell death transcription, DNA-templated protein phosphorylation positive regulation of apoptotic process protein autophosphorylation apoptotic process MAPK cascade Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	4293	338372
Ensembl	ENSG00000006432	ENSMUSG00000042724
UniProt	P80192	Q3U1V8
RefSeq (mRNA)	NM_001284230 NM_001284231 NM_001284232 NM_033141	NM_001174107 NM_177395
RefSeq (protein)	NP_001271159 NP_001271160 NP_001271161 NP_149132	NP_001167578 NP_796369
Location (UCSC)	Chr 14: 70.72 – 70.81 Mb	Chr 12: 81.77 – 81.83 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

Mitogen-activated protein kinase kinase kinase 9 is an enzyme that in humans is encoded by the MAP3K9 gene.^[5]